Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958? Semiconservative ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...